Question: Who Is Most Likely To Get Charcot Marie Tooth Disease?

Is CMT considered a disability?

Medically Qualifying Under A Disability Listing: CMT is a form of peripheral neuropathy, meaning it affects the nerves and muscles in the arms, legs, hands, and feet.

The Social Security Administration (SSA) has a standard disability listing for this type of neurological disorder..

What does a Charcot foot look like?

When the midfoot is involved in Charcot foot, the arch collapses, which rounds the bottom of the foot. This is called a rocker-bottom foot deformity. Depending on the location of the bone break, the toes can start to curve under like claws or the ankle can become deformed and unstable.

How do you test for Charcot Marie Tooth disease?

To diagnose CMT, your doctor will order tests to help determine the cause and extent of your nerve damage. These tests may include a nerve conduction study, electromyography, nerve biopsy, and genetic testing. A nerve conduction study can test the function of electrical signals in your nerves.

Is CMT more common in males or females?

The condition affects an equal number of males and females. CMT hereditary neuropathy is the most common inherited neurological disorder affecting more than 250,000 Americans. Since this condition is frequently undiagnosed, misdiagnosed or diagnosed very late in life, the true number of affected persons may be higher.

How is Charcot Marie Tooth disease inherited?

CMTX is inherited in an X-linked dominant pattern . A condition is considered X-linked if the mutated gene that causes the disorder is located on the X chromosome. The inheritance is dominant if one copy of the altered gene is sufficient to cause the condition.

Can CMT be passed from father to daughter?

This change is called a mutation. Some genetic mutations are hereditary, meaning they can be passed down from a parent to their child. CMT is caused by hereditary genetic mutations. But just because someone has CMT doesn’t mean they got it from one of their parents.

Can CMT skip a generation?

CMT does not skip generations genetically. For people with autosomal dominant and X-linked conditions, a person will either have the condition or not. If a parent has CMT that has been genetically confirmed, a child can be tested when that child is at least 18 years of age and with appropriate genetic counseling.

Can CMT make you tired?

Fatigue is a common symptom in CMT. A study, published in the Journal of Neurology in 2010 and based on questionnaire given patients and an age- and sex-matched control group, reported that fatigue levels were significantly higher in people with CMT. Fatigue in CMT can be due to a number of reasons.

What is Charcot Marie Tooth type 2?

Charcot-Marie-Tooth disease type 2 (CMT2) is a type of CMT with genetic defects that disrupt the structure and function of the axons of the peripheral nerves. So, CMT2 often is referred to as “axonal CMT.” CMT2 is less common than CMT1 and accounts for about one-third of all dominant CMT cases.

Is Charcot Marie Tooth painful?

Because CMT causes damage to sensory nerve fibers (axons), people with CMT can feel tingling and burning sensations in the hands and feet, usually causing only mild discomfort but sometimes causing pain. The sense of touch is diminished, as is the ability to sense changes in temperature.

Is Charcot Marie Tooth a form of MS?

Charcot-Marie-Tooth disease type X (CMTX) may increase the risk of developing multiple sclerosis (MS), the most common central nervous system inflammatory demyelinating disease, according to data from a Greek study.

Can CMT affect your eyes?

CMT Type 6 involves development of optic atrophy with loss of vision or blindness, muscle atrophy and weakness, loss of sensation, and balance and gait difficulties. Depending on the genetic cause of the CMT Type 6, there may be other symptoms including delayed learning.

What does Charcot Marie Tooth disease look like?

Charcot-Marie-Tooth disease is also called hereditary motor and sensory neuropathy. Charcot-Marie-Tooth disease results in smaller, weaker muscles. You may also experience loss of sensation and muscle contractions, and difficulty walking. Foot deformities such as hammertoes and high arches also are common.

At what age does CMT present?

The age of onset of CMT can vary anywhere from young childhood to the 50s or 60s. Symptoms typically begin by the age of 20. For reasons unknown as of 2004, the severity in symptoms can also vary greatly, even among members of the same family .

Does Charcot Marie Tooth affect the brain?

Unlike other neurological disorders, CMT usually isn’t life-threatening, and it almost never affects the brain. It causes damage to the peripheral nerves — tracts of nerve cell fibers that connect the brain and spinal cord to muscles and sensory organs.